Unicentric Castleman’s disease involving central nervous system rare entity

Castleman’s disease (CD) is a rare disease primarily involving lymph nodes and lymphatic system. Other synonyms used for the C follicular lymph node hyperplasia disorder which means there is an abnormal overgrowth of cells of the lymphatic syste in many ways to lymphomas (cancers of lymph nodes). Even though CD is not officially a true cancer, one form of this disease (known as lymphoma. In fact we can call it as premalignant eventually develop lymphomas. Multi recent years, it’s become clear that another virus, known as sarcoma herpes virus (KSHV), is often found in the lymph node cells of people with multi CD. In fact, HHV-8 is found in the lymph nodes of nearly all CD patients who are HIV positive. We present a case of unicentric plasma cell type of C (CNS) or brain parenchyma in a young male patient which is a rare occurrence.